论文 · 综述
寻找塑造人类面孔的基因：初步成功与未来挑战
Hunting for genes that shape human faces: Initial successes and challenges for the future
作者：Seth M Weinberg, Jasmien Roosenboom, John R Shaffer, Mark D Shriver, Joanna Wysocka, Peter Claes
Orthod Craniofac Res · 2019年5月 · Weinberg 等 6 位作者
不需要生物学背景，多打比方
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摘要Abstract
There is ample evidence from heritability studies, genetic syndromes and experimental animal models that facial morphology is strongly influenced by genes. In this brief review, we present an up-to-date overview of the efforts to identify genes associated with the size and shape of human facial features. We discuss recent methodological advances that have led to breakthroughs, but also the multitude of challenges facing the field. We offer perspective on possible applications of this line of research, particularly in the context of the precision genomics movement.
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