澳大利亚公众对类器官研究与使用的态度探究：一项横断面研究
Exploring Australian Public Attitudes Toward Organoid Research and Use: A Cross-Sectional Study
类器官技术为研究人体生物学和开发新疗法提供了新途径，但公众是否了解、是否接受这项技术此前几乎无人调查，而这直接关系到技术能否被合乎伦理且公平地应用。研究者对 502 名澳大利亚人做了首次全国调查，评估他们对类器官的认知、知识和接受度。结果显示，人们对干细胞较熟悉，但对类器官基本陌生；观看一段简短解说视频后，参与者的概念理解更准确，但客观知识仍然有限。总体支持率很高，愿意为干细胞或类器官研究捐献细胞的人比实际捐过的人更多；接受度与对动物实验的态度、知识水平及部分社会人口学因素相关。作者强调公众的支持是有条件的，需要透明的治理、清晰的知情同意和包容性的沟通。
为什么推荐给您：首次全国性公众态度调查，为类器官治理和知情同意提供新证据。
不需要生物学背景，多打比方
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摘要Abstract
Organoid technologies offer promising new ways to study human biology and develop innovative therapies. While their scientific potential is clear, public awareness and acceptability remain largely unexplored - critical factors for ethical and equitable implementation. We conducted the first national survey of Australians (N = 502) to assess awareness, knowledge, attitudes, and acceptability of organoid technology. Awareness of stem cells was high, but organoids were largely unfamiliar. After a brief explanatory video, participants appeared to have more accurate conceptual framing (e.g., organoids as "research tools" and "mini-organs"), though objective knowledge remained limited. There was strong support for organoids, and more people expressed willingness to donate cells for stem cell or organoid research than have previously done so. Acceptability was correlated with attitudes toward animal research, knowledge, and some sociodemographic factors. Overall, public endorsement of organoid technology appears high but conditional, underscoring the need for transparent governance, clear consent, and inclusive communication.